According to The $\Delta$ G $\degree$ ^' , Which of the Following Exergonic Reactions Is Most

Multiple Choice

According to the $\Delta$ G $\degree$ ^' , which of the following exergonic reactions is most likely irreversible under normal cellular conditions and is considered to be the rate-limiting step of the citrate cycle?

A) "citrate synthase"
B) "fumarase"
C) "isocitrate dehydrogenase"
D) " $\alpha$ -ketoglutarate dehydrogenase"