In Glycolysis, Fructose 1,6-Bisphosphate Is Converted to Two Products with a Standard

Multiple Choice

In glycolysis, fructose 1,6-bisphosphate is converted to two products with a standard free-energy change ( $\Delta$ G ^' $\degree$ ) of 23.8 kJ/mol. Under what conditions (encountered in erythrocytes) will the free-energy change ( $\Delta$ G) be negative, enabling the reaction to proceed to products?

A) The free-energy change will be negative if the concentrations of the two products are high relative to that of fructose 1,6-bisphosphate.
B) The reaction will not go to the right spontaneously under any conditions because the $\Delta$ G ^' $\degree$ is positive.
C) Under standard conditions, enough energy is released to drive the reaction to the right.
D) The free-energy change will be negative when there is a high concentration of fructose 1,6-bisphosphate relative to the concentration of products.