Use the Following Model of a Eukaryotic Transcript to Answer

Multiple Choice

Use the following model of a eukaryotic transcript to answer the question.E_1-4 refer to the exons,and I_1-3 refer to the introns in the pre-mRNA transcript.
5' UTR E₁ I₁ E₂ I₂ E₃ I₃ E₄ UTR 3'
Suppose that exposure to a chemical mutagen results in a change in the sequence that alters the 5' end of intron 1 (I₁) .Which of the following results might occur?

A) loss of the gene product
B) loss of E₁
C) premature transcriptional termination
D) inclusion of I₁ in the mRNA