A Mutation That Results in a Single Amino Acid Substitution

Multiple Choice

A mutation that results in a single amino acid substitution in the active site of an enzyme may have which of the following consequences?

A) It may alter the ability of a noncompetitive inhibitor to bind to the enzyme.
B) It may alter the ability of an allosteric regulator to effect enzyme activity.
C) It may change the substrate specificity of the enzyme.
D) It may change the ∆G for the original reaction catalyzed by the enzyme.