As a Protein Is Made, the Polypeptide Is in an Extended

Essay

As a protein is made, the polypeptide is in an extended conformation, with every amino acid exposed to the aqueous environment.Although both polar and charged side chains can mix readily with water, this is not the case for nonpolar side chains.Explain how hydrophobic interactions may play a role in the early stages of protein folding, and have an influence on the final protein conformation.