You Have Generated Antibodies That Recognize the Extracellular Domain of the Ca²⁺-Pump.Adding

Multiple Choice

You have generated antibodies that recognize the extracellular domain of the Ca²⁺-pump.Adding these antibodies to animal cells blocks the active transport of Ca²⁺ from the cytosol into the extracellular environment.What do you expect to observe with respect to intracellular Ca²⁺?

A) Ca²⁺-pumps in vesicle membranes keep cytosolic calcium levels low.
B) Ca²⁺-pumps in the endoplasmic reticulum membrane keep cytosolic calcium levels low.
C) Ca²⁺-pumps in the Golgi apparatus keep cytosolic calcium levels low.
D) Ca²⁺ concentrations in the cytosol increase at a steady rate.