For each of the following sentences, fill in the blanks with the best word or phrase selected from the list below.Not all words or phrases will be used; each word or phrase should be used only once.

\begin{array}{lll}\text { anaphase } & \text { differentiation } & \text { myostatin } \\\text { annihilation } & \mathrm{G}_{0} & \text { nourishment } \\\text { arrestase } & \mathrm{G}_{1} & \text { nutrition } \\\text { Bcl2 } & \mathrm{G}_{2} & \text { phosphatases } \\\text { biosynthetic } & \text { growth factors } & \text { proliferation } \\\text { cyclin } & \text { interphase } & \text { receptor } \\\text { cascades } & \text { ligand } & \mathrm{S} \\\text { caspase } & \mathrm{M} & \text { survival factors } \\\text { Cdk } & \text { mitogens } & \text { transcription }\end{array}

The survival, __________, and size of each cell in an animal are controlled by extracellular signal molecules secreted by neighboring and distant cells.Many of these signal molecules bind to a cell-surface __________ and trigger various intracellular signaling pathways.One class of signal molecules, called __________, stimulates cell division by releasing the molecular brakes that keep cells in the __________or __________ phase of the cell cycle.Members of a second class of signal molecules are called __________, because they stimulate cell growth and an increase in cell mass.The third class of signal molecules, called __________, inhibits apoptosis by regulating members of the __________ family of proteins.In addition to such stimulatory factors, some signal proteins, such as __________ act negatively on other cells, inhibiting their survival, growth, or proliferation.

Which of the Following Statements About Kinetochores Is TRUE

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