You Have Isolated a Mutant in Which a Fraction of the New

Essay

You have isolated a mutant in which a fraction of the new cells die soon after cell division and a fraction of the living cells have an extra copy of one or more chromosomes.When you grow the cells under conditions in which they transit the cell cycle more slowly, the defect disappears, suggesting that the mitotic spindle and segregation machinery are normal.Propose a basis for the defect.