Would Antibodies Produced by a Patient in Response to Infection

Multiple Choice

Would antibodies produced by a patient in response to infection be monoclonal, or polyclonal?

A) Since the infection is from only a single agent/microbe, the antibodies would be monoclonal.
B) Since a single pathogen has multiple epitopes, the responding antibodies to a whole pathogen would be polyclonal.
C) Since the pathogen would most likely mutate slightly during the infection (producing different epitopes) , the responding antibodies would be polyclonal.
D) Since the pathogen would acquire and modify self-antigens during the infectious process, the antibodies produced during the response would be polyclonal.
E) Since only one B cell is ever activated in response to a pathogen, the antibodies that are produced would be monoclonal.