Which Statement Is TRUE

Multiple Choice

Which statement is TRUE?

A) In adulthood, nearly all individuals with Down syndrome develop amyloid plaques and neurofibrillary tangles.
B) In adulthood, nearly all individuals with Down syndrome develop cognitive impairments similar to those seen in patients with Alzheimer's disease.
C) The APOE gene has been implicated in both Down syndrome and Alzheimer's disease.
D) The PS1 gene has been implicated in both Down syndrome and Alzheimer's disease.