Base-Modifying Chemicals Such as Aflatoxin B₁ or Nitrosoguanidine Cause Mutations

Multiple Choice

Base-modifying chemicals such as aflatoxin B₁ or nitrosoguanidine cause mutations by

A) increasing the likelihood of depurination.
B) causing double-stranded breaks in the DNA sugar-phosphate backbone.
C) causing mispairing during DNA replication.
D) causing pyrimidine dimers.
E) increasing the likelihood of depurination or causing mispairing during DNA replication.