Multiple Choice
In a GWAS experiment, 500,000 SNPs across the genome are genotyped in thousands of Case and Control individuals.Which statistical analysis should be applied and why?
A) A chi-square test for goodness of fit will test the null hypothesis that the distribution of each SNP allele is the same in Cases and Controls.
B) A chi-square test for goodness of fit can be used because this is a small number of SNPs.
C) A chi-square test for independence should be used to test the null hypothesis that the distribution of each SNP allele is the same in Cases and Controls.
D) A chi-square test for independence should be used to test the null hypothesis that each SNP is linked to a QTL.
Correct Answer:
Verified
Correct Answer:
Verified
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