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Each Human α-Globin Locus Contains Two α-Globin Genes, α1 and α2

Question 3

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Each human α-globin locus contains two α-globin genes, α1 and α2, and most individuals have two copies of the locus.Which of the genotypes would result in the most severe phenotype? (A"-" represents a deletion allele. )


A) α1 α1 / α2 α2
B) α1 - / α2 -
C) α1 α1 / - -
D) α1 - / α2 α2
E) α1 - / - -

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