During Meiotic Prophase in a Eukaryotic Cell, Spo11 Initiates Recombination

Multiple Choice

During meiotic prophase in a eukaryotic cell, Spo11 initiates recombination by causing a double-strand break in DNA between Gene A and Gene B on one sister chromatid.Which of these events will occur prior to formation of a Holliday junction?

A) A heteroduplex forms due to pairing of Gene A and Gene B.
B) Resolvase cuts all four chromatids.
C) Spo11 causes a double-strand break in a nonsister chromatid.
D) Strand invasion causes one strand of the uncut chromatid to form a D loop.
E) Branch migration lengthens the heteroduplex region to include Gene A and Gene B.