Amplification Steps in the Complement Pathways Occur

Multiple Choice

Amplification steps in the complement pathways occur

A) in the classical pathway with C1 cleaving multiple molecules of C4 and multiple C2 for every C1 and C4; in the alternative pathway with the C3b of other pathways becoming C3 convertase; and then the C3b becoming part of a C5 convertase
B) in all pathways with all the C3 convertases making multiple C3a +C3b
C) with C9 polymerization
D) all of the above
E) A and B only