You Are Working to Characterize a Novel Protein in Mice

Multiple Choice

You are working to characterize a novel protein in mice.Analysis shows that high levels of the primary transcript that codes for this protein are found in tissue from the brain, muscle, liver, and pancreas.However, an antibody that recognizes the C-terminal portion of the protein indicates that the protein is present in brain, muscle, and liver, but not in the pancreas.What is the most likely explanation for this result?

A) The gene that codes for this protein is not transcribed in the pancreas.
B) The transcript is immediately degraded in the pancreas.
C) The transcript receives a 5' cap in the pancreas.
D) Alternative splicing in the pancreas creates a protein missing the domain that the antibody recognizes.