Somatic Cancer Cells Often Are Unstable and Divide Inappropriately (Divide

Multiple Choice

Somatic cancer cells often are unstable and divide inappropriately (divide when they should not be dividing) . In addition such cells often contain losses of some chromosomes and extra copies of other chromosomes. Defects in which of the following may be partially responsible for the aberrant behavior of cancer cells? (Select all that apply.)

A) spindle-assembly checkpoint
B) G₁/S checkpoint
C) homologous chromosome pairing
D) crossing over