You Are Interested in a Particular Segment of Rhinoceros DNA

Multiple Choice

You are interested in a particular segment of rhinoceros DNA and would like to clone it into a cloning plasmid. You have the following restriction map of the region that includes the DNA of interest and the plasmid (E = EcoRI, H = HindIII, X = XbaI, S = SphI, N = NotI) . Which restriction enzymes would you choose to clone the DNA of interest into the cloning vector?

A) E and H
B) S
C) X and N
D) S and N