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Achondroplasia Is a Form of Dwarfism That Is Inherited in Humans

Question 92

Multiple Choice

Achondroplasia is a form of dwarfism that is inherited in humans as an autosomal dominant disorder. A survey in a small country showed that, within a two-year period, there were 12 children with normal parents born with this disorder out of a total of 420,000 births. What is the mutation rate in mutations/locus/generation?


A) 1.4 × 10-5
B) 2.8 × 10-6
C) 2.5 × 10-5
D) 2.8 × 10-5
E) 7.4 × 10-6

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