Given the Following Figure, What Would Be the Effect of a Mutation

Multiple Choice

Given the following figure, what would be the effect of a mutation that occurred in the insulator that prevented the binding of the insulator-binding protein?

A) Both Enhancer 1 and Enhancer II would be able to stimulate the transcription of Genes A and B.
B) Enhancer I would no longer be able to stimulate the transcription of Gene B.
C) Enhancer I will be able to hypermethylate Gene B.
D) As long as the insulator sequence is not deleted, there will be no change in the transcription regulation of Gene A or B.
E) Enhancer II will no longer be able to stimulate the transcription of Gene A.