In Addition to an Increase in Sensitivity to Glutamate, the Binding

Multiple Choice

In addition to an increase in sensitivity to glutamate, the binding of large amounts of glutamate to its receptors on the postsynaptic membrane also

A) affects other synapses that are close to the first.
B) can overwhelm the synapse.
C) stimulates the release of a paracrine messenger that further increases glutamate release.
D) directly causes more NMDA channels to open.
E) stimulates presynaptic autoreceptors and enhances its release.