The DNA Sequence of a Portion of Gene in a Wild-Type

Multiple Choice

The DNA sequence of a portion of gene in a wild-type organism is TTACCATATTCACCC, and the corresponding peptide sequence is Leu-Pro-Tyr-Ser-Pro. The corresponding gene fragment in a phenotypic variant of the organism is TTACCATATTCACCC and the peptide sequence is Leu-Pro-Cys-Ser-Pro. This is an example of a(n) mutation (type) resulting in a
Mutation (effect) .

A) base substitution; silent
B) base substitution; missense
C) deletion; missense
D) insertion; nonsense
E) base substitution; nonsense