Which of the Following Is the Best Explanation for Why

Multiple Choice

Which of the following is the best explanation for why hypersecretion of GH in adults does not lead to significant increases in height?

A) GH does not affect bone growth.
B) Epiphyseal plates are closed in adults.
C) Adult bones lack osteoblasts.
D) The physical size of adult bones prevents further growth.
E) Adults lack somatomedins necessary for bone lengthening.