Why Is Sequencing of Eukaryotic Genomes More Difficult Than Sequencing

Multiple Choice

Why is sequencing of eukaryotic genomes more difficult than sequencing genomes of bacteria or archaea?

A) It is due to the large size of eukaryotic proteins.
B) Eukaryotic genomes contain sequences for hard-to-find proteins.
C) There is a high proportion of G-C base pairs in eukaryotic DNA, which makes sequencing difficult to complete.
D) The large size of eukaryotic genomes and the large amount of eukaryotic repetitive DNA make sequencing difficult.