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Assume That a Series of Compounds Has Been Discovered in Neurospora.Compounds

Question 24

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Assume that a series of compounds has been discovered in Neurospora.Compounds A-F appear to be members of an enzyme pathway.Several mutations have been identified and each of strains 1-4 contains a single mutation.Shown below are five possible pathways.Choose the pathway that best fits the data presented.[Growth in minimal media with supplements is shown by (+) ,no growth is shown by (o) .]  strain ABCDEF1 o  o  o +++2 o  o  o  o ++3o o  o  o + o 4 o  o ++++\begin{array}{|c|c|c|c|c|c|c|}\hline\text { strain }&A&B&C&D&E&F\\\hline 1& \text { o } & \text { o } & \text { o } &+ & + & + \\\hline 2& \text { o } & \text { o } & \text { o } &\text { o } & + & + \\\hline 3& \mathrm{o} & \text { o } & \text { o } & \text { o } & + &\text { o } \\\hline 4& \text { o } &\text { o } & + & + & + & + \\\hline\end{array}


A) A ? B ? C ? D ? E ? F
B) A ? B ? C ? F ? D ? E
C) F ? B ? C ? D ? A ? E
D) A ? B ? C ? D ? F ? E
E) A ? B ? F ? E ? C ? D

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