HIV, the Virus Which Causes AIDS, Interacts with Two Receptors

Multiple Choice

HIV, the virus which causes AIDS, interacts with two receptors on the host cell membrane: CD4 and CCR5. A small percentage of individuals have a genetic mutation which causes their cells to lack CCR5. These individuals will never develop AIDS nor are they able to pass HIV on to others. Which part of viral replication is being blocked by the lack of a receptor?

A) The host cell enzymes are unable to replicate the HIV genome.
B) The virus components cannot be assembled into new virions.
C) Endocytosis is being prevented.
D) HIV cannot attach to the host cell without the proper membrane receptor.
E) Newly assembled virions cannot be released from the host cell.