Which of the Following About the Pathogenesis of Rabies Is

Multiple Choice

Which of the following about the pathogenesis of rabies is false?

A) the rabies virus lyses host cells which explains neurological symptoms including pharyngeal spasms, confusion, loss of coordination, delirium, and the characteristic hydrophobia
B) the virus rapidly travels through neurons, replicating and spreading to the CNS
C) after invading brain cells, rabies spreads back out into the PNS where it replicates and is shed from tissues that are well supplied with nerves, including the salivary glands
D) the virus slowly replicates in the muscle cells leading to a long incubation period that lasts from two months to a year
E) a diagnostic sign of rabies is the formation of Negri bodies, small clusters of virus inside the neurons