Increasing Cytosolic [Ca²⁺] Is More Useful as a Signaling Mechanism

Multiple Choice

Increasing cytosolic [Ca²⁺] is more useful as a signaling mechanism than Increasing [Na⁺] or [K ⁺] or [Cl^-] because

A) Far fewer Ca²⁺ ions need to flow because intracellular [Ca²⁺] is so low
B) Ca²⁺ can bind to specific proteins
C) Unlike the other ions, Ca²⁺ can activate phosphorylation of proteins
D) The Increase in [Ca²⁺] can be short-lived
E) All of the above