Define the Terms Effective Dose and Lethal Dose

Question

Examlex · Accepted Answer

The Answer is The effective dose (ED) is the amount of a drug or treatment that produces the desired effect in a certain percentage of the population. It is often expressed as the dose required to achieve a specific therapeutic effect in 50% of the population (ED50). The lethal dose (LD) is the amount of a drug or treatment that causes death in a certain percentage of the population. It is often expressed as the dose that is lethal to 50% of the population (LD50).

The therapeutic index of a drug is a measure of its safety and efficacy. It is calculated by dividing the lethal dose by the effective dose (TI = LD50/ED50). A higher therapeutic index indicates that the drug is safer, as it means that the effective dose is much lower than the lethal dose. This means that there is a wider margin of safety between the dose that produces the desired effect and the dose that could be lethal.

By using the effective dose and lethal dose to calculate the therapeutic index of a drug, healthcare professionals can determine the safety and efficacy of the drug. This information is crucial for determining the appropriate dosage and monitoring for potential adverse effects in patients. It also helps in comparing the safety profiles of different drugs and making informed decisions about their use in clinical practice.

Define the Terms Effective Dose and Lethal Dose

Essay

Correct Answer:
Answered by ExamLex AI

Define the Terms Effective Dose and Lethal Dose

Essay

Correct Answer:Answered by ExamLex AIShow Answer

Correct Answer:
Answered by ExamLex AI