What Must Eukaryotes Do to Initiate Transcription of a Gene

Multiple Choice

What must eukaryotes do to initiate transcription of a gene?

A) Recruit general transcription factors to produce an open complex and then recruit RNA Polymerase.
B) Bind RNA Polymerase to displace histone proteins that binding DNA in the promoter region.
C) Bind transcription factors from enhancer sequences to the RNA Polymerase.
D) Recruit the transcription factors and RNA Polymerase that compose the pre- initiation complex.
E) Open the DNA template and then bind RNA Polymerase at the transcriptional initiation site.