Isabel Had Been Taking Valium, a Benzodiazepine, for a Few

Multiple Choice

Isabel had been taking Valium, a benzodiazepine, for a few years to calm her nerves and help her sleep.She had her dosage increased by her doctor because her previous dosage wasn't helping her sleep at night anymore.One night, she went out with her husband for his company's annual Christmas party.She had never been much of a drinker, but that evening she wanted to enjoy a few cocktails.She was very careful not to mix her Valium with alcohol, as her doctor had warned her.Towards the end of the evening, Isabel realized that she had had at least 5 cocktails and didn't feel drunk at all.Which term may best describe why this happened?

A) Cross dependence
B) Cross tolerance
C) Up-regulation
D) Co-transmission