With Regard to Cancer Cells in the Process of Metastasis

Multiple Choice

With regard to cancer cells in the process of metastasis to secondary sites, which of the following statements is NOT correct?

A) If they enter via lymphatics, cancer cells may multiply in regional lymph nodes.
B) Many cells from the primary mass may enter circulation.
C) The population of cancer cells is heterogeneous.
D) Very few cancer cells survive the bloodstream.
E) The population of cancer cells in the bloodstream is monoclonal.