Multiple Choice
How do the pKa values of an ionizable side chain compare when the amino acid is free versus when it is in a polypeptide chain?
A) The pKa of the side chain is independent of whether the amino acid is in a polypeptide chain or is free.
B) The pKa of the side chain is always lower for the free amino acid.
C) The pKa of the side chain may be lower or higher in a polypeptide chain due to weaker inductive effects and differences in their microenvironments.
D) The pKa of the side chain is usually higher in a polypeptide chain due to stabilization from nearby residues in the three-dimensional structure.
Correct Answer:
Verified
Correct Answer:
Verified
Q2: Ultraviolet (UV)light can be used to estimate
Q19: The RS system of nomenclature describes<br>A) amino
Q20: The last common ancestor of modern organisms
Q22: Which technique is most sensitive and accurate
Q22: Affinity chromatography can be used to save
Q24: During the fractionation process which of the
Q27: In a biochemistry laboratory a student added
Q46: Most proteins contain an approximately equal amount
Q68: Cation-exchange resins have negatively charged groups covalently
Q73: The liquid that emerges from the bottom