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In the Initial Test of the Salk Vaccine for Polio

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In the initial test of the Salk vaccine for polio, 400,000 children were selected and divided into two groups of200,000. One group was vaccinated with the Salk vaccine while the second group was vaccinated with aplacebo. Of those vaccinated with the Salk vaccine, 33 later developed polio. Of those receiving the placebo, 115later developed polio. Test the hypothesis that the Salk vaccine is effective in lowering the polio rate. Useα = 0.01.

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