A Pharmaceutical Company Wishes to Test a New Drug with the Expectation

Essay

A pharmaceutical company wishes to test a new drug with the expectation of lowering cholesterol levels. Ten subjects are randomly selected and their cholesterol levels are recorded. The results are listed below. The subjects were placed on the drug for a period of 6 months, after which their cholesterol levels were tested again. The results are listed below. (All units are milligrams per deciliter.) Use the Wilcoxon signed rank test to test the company's claim that the drug lowers cholesterol level $\text { Use } \alpha = 0.05$ $$\begin{array} { l c c c c c c c c c c } \hline \text { Subject } & 1 & 2 & 3 & 4 & 5 & 6 & 7 & 8 & 9 & 10 \\\hline \text { Before } & 230 & 219 & 204 & 262 & 177 & 260 & 186 & 254 & 175 & 268 \\\text { After } & 215 & 214 & 212 & 252 & 172 & 260 & 156 & 236 & 173 & 253 \\\hline\end{array}$$