A Nurse Working in the Chemotherapy Outpatient Department Is Providing

Multiple Choice

A nurse working in the chemotherapy outpatient department is providing antiemetic therapy using Zofran (ondansetron) . The ordered dose is 32 mg. Which of the following actions should the nurse take to optimize the efficacy of the medication?

A) Provide the dose as an intramuscular injection 10 min prior to starting chemotherapy.
B) Provide the dose undiluted intravenously over 2 min just prior to starting chemotherapy.
C) Provide the dose diluted in 50 mL of D5W infused intravenously over 15 min at least 30 min prior to starting chemotherapy.
D) Provide the dose diluted in 50 mL of 0.9 NaCl infused intravenously over 5 min, 60 min prior to starting chemotherapy.