Mice with Mutations That Prevent the Clustering of Telomeres in Leptotene

Multiple Choice

Mice with mutations that prevent the clustering of telomeres in leptotene develop defects. What do these defects suggest the purpose of clustering telomeres may be?

A) termination of synapsis
B) facilitation of synapsis, genetic recombination and gamete formation
C) prevention of chromosome alignment until synapsis begins
D) spread of chromosomes out in preparation for synapsis
E) initiation of the dissolution of the nuclear envelope