Why Does It Appear That Each Origin Can Only Be

Multiple Choice

Why does it appear that each origin can only be activated once per cell cycle?

A) MCM proteins are displaced from the DNA after replication and cannot reassociate with a replication origin that has already fired.
B) The ORC is denatured after replication and cannot return to the DNA.
C) The DNA becomes naked until the next round of cell division.
D) MCM proteins reassociate with DNA immediately and prevent further replication from that DNA.
E) MCM proteins bind to other proteins in the cytoplasm; together they actively inhibit further replication.