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Bardet‐Biedl Syndrome (BBS)is Caused by Mutations in Any One of a Number

Question 45

Multiple Choice

Bardet‐Biedl syndrome (BBS) is caused by mutations in any one of a number of genes that affect protein trafficking into cilia. Persons afflicted with BBS exhibit a remarkable range of abnormalities, like polydactyly, obesity, kidney disease, etc. These disparatesymptoms are thought to reflect the function of cilia ________________.


A) as sensors for a magnetic field
B) aslocomotory organelles
C) as sources of flagella
D) as binding sites for actin
E) as antennas to receive signals that regulate development and physiology

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