What Do Studies Suggest Governs the "Decision" to Destroy a Defective

Multiple Choice

What do studies suggest governs the "decision" to destroy a defective protein that has been unable to fold correctly and has been in the ER for an extended period of time?

A) a fast-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein
B) a slow-acting ER enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein
C) a fast-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein
D) a slow-acting nuclear enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein
E) a slow-acting cytoplasmic enzyme that trims a mannose residue from an exposed end of the oligosaccharide of a protein