Why Does Targeting Glucocerebrosidase to Lysosomes in Macrophages Serve as a Treatment

Multiple Choice

Why does targeting glucocerebrosidase to lysosomes in macrophages serve as a treatment for Gaucher's disease?

A) Glucocerebrosidase is normally denatured in the lysosomes.
B) Glucocerebrosidase is delivered to the precise sites in the cell where the deficiency is manifested, correcting the deficit.
C) Glucocerebrosidase denatures the cytoplasm from its location in the lysosomes, correcting the deficit.
D) Glucocerebrosidase binds to the outer lysosome surface and breaks down glycogen in the cytoplasm.
E) Glucocerbrosidase is supposed to digest most of the enzymes in the lysosome.