L1 Is an IgSF Molecule That Has Been Shown to Be

Multiple Choice

L1 is an IgSF molecule that has been shown to be important in neural development; it is thought that it may be involved in axon growth within the embryonic nervous system. What evidence supports this statement?

A) L1 mutants always die.
B) L1 mutants show deficits in their vision.
C) People who die of L1-deficiency are often missing two large nerve tracts connecting brain/spinal cord regions.
D) People who die of L1-deficiency are often missing a significant portion of their brain.
E) People who die of L1-deficiency are often missing a significant portion of their spinal cord.