In Cells Relying Exclusively Upon Glycolysis and Substrate-Level Phosphorylation for ATP

Multiple Choice

In cells relying exclusively upon glycolysis and substrate-level phosphorylation for ATP production, why is the production of reduced intermediates from pyruvate so essential?

A) Reduction of pyruvate also allows for the reduction of NADH, providing NAD⁺ which is an essential substrate for the activity of glyceraldehyde phosphate dehydrogenase.
B) Reduction of pyruvate allows for the oxidation of NADH, providing NAD⁺ which is an essential substrate for the activity of glyceraldehyde phosphate dehydrogenase.
C) Reduction of pyruvate also allows for the reduction of NADH, providing NAD⁺ which is an essential substrate for the activity of triose phosphate isomerase.
D) Reduction of pyruvate allows for the oxidation of NADH, providing NAD⁺ which is an essential substrate for the activity of triose phosphate isomerase.