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Marfan Syndrome in Humans Is Caused by an Abnormality of the Connective

Question 31

Multiple Choice

Marfan syndrome in humans is caused by an abnormality of the connective tissue protein fibrillin. Patients are usually very tall and thin, with long spindly fingers, curvature of the spine, sometimes weakened arterial walls, and sometimes ocular problems, such as lens dislocation. Which of the following would you conclude about Marfan syndrome from this information?


A) It is recessive.
B) It is dominant.
C) It has a late age of onset (> 60) .
D) It is pleiotropic.
E) It is epistatic.

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