Tetrodotoxin Blocks Voltage-Gated Sodium Channels, and Ouabain Blocks Sodium-Potassium Pumps

Multiple Choice

Tetrodotoxin blocks voltage-gated sodium channels, and ouabain blocks sodium-potassium pumps. If you added both tetrodotoxin and ouabain to a solution containing neural tissue, what responses would you expect?

A) immediate loss of resting potential
B) immediate loss of action potential with gradual shift of resting potential
C) slow decrease of resting potential and action potential amplitudes
D) No effect; the substances counteract each other.