Recommend What Type of Data Should Be Collected and Analyzed

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The Answer is A systems biology approach integrates multiple methods and fields to model or analyze a problem. One approach would be to compare the genome and the proteome of non-pathogenic and pathogenic strains of a particular species to find the genes and proteins that are different and may be related to pathogenicity. This research would involve 3rd or 4th generation sequencing, 2D polyacrylamide gel electrophoresis of proteins, and bioinformatics to process and analyze all the data. Further experimentation could involve genetic manipulations to investigate the effect of removing or mutating the implicated genes and biochemical characterization of the implicated proteins. (Answers could vary significantly, but any reasonable discussion of how various ʺ-omicʺ techniques and methods could be applied to this problem could be acceptable as long as the discussion is consistent and logical, linking the appropriate data types and methods to detect differences between pathogenic and nonpathogenic organisms. The answer should include the definition of systems biology.)

Recommend What Type of Data Should Be Collected and Analyzed

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Recommend What Type of Data Should Be Collected and Analyzed

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