(Scenario II)

Multiple Choice

(Scenario II) . Suppose the researchers wanted to examine whether e-cigs were indeed less harmful than cigarettes to adolescents' health, and proposed to recruit 1000 10^th graders who would be randomly assigned to use e-cigs or cigarettes for 6 months after which they would be examined by a medical doctor. Upon receiving this proposal, the IRB at the researchers' university quickly denied their application. Which of the following reasons for denying the application is most likely?

A) It is not just to recruit only 10^th graders.
B) The researchers lack of requiring both parental consent and participant assent.
C) The cost-benefit analysis suggested the study was too risky and reward too small.
D) Psychological harm to the participants was too great.