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What Is the Pathogenesis of MAHA

Question 13

Multiple Choice

What is the pathogenesis of MAHA?


A) Microthrombi and fibrin formed on damaged endothelial cells trap and break red cells.
B) Chemicals or heat destroy red blood cells (RBCs) .
C) The spleen sequesters red cells in an attempt to remove abnormal inclusions.
D) Antibodies that activate complement are formed and destroy the red cell membrane.

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