Aram Volunteers at a Nursing Home, Where He Reads and Writes

Multiple Choice

Aram volunteers at a nursing home, where he reads and writes letters for residents who can't do those things for themselves. Though he visits every week, Mr. Larue never remembers him, and he has to introduce himself each time they interact. One of the nurses explains that Mr. Larue has Alzheimer's disease (AD) . The most characteristic changes in the brain associated with AD are

A) plaque and tartar.
B) threads and tangles.
C) threads and tartar.
D) plaques and tangles.
E) threads and plaques.