Enzymes Work with at Least Three Mechanisms

Multiple Choice

Enzymes work with at least three mechanisms. Which of the following is NOT a mechanism by which enzymes function?

A) by putting reactants in close proximity to each other
B) by altering the free energy (G) of the reaction
C) by orienting the reactants so they are positioned to favour the transition state
D) by altering the immediate environment of the reactants to promote reactant interactions